Roxana Hotel Accommodation

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
14 Nov - 15 Nov
Tomorrow
15 Nov - 16 Nov
Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov

Where to stay in Roxana?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Roxana on Hotels.com. These Roxana hotels consistently deliver on quality, location and traveller experience. Last updated on 14 November 2026.
A buffet with various food items, including omelets and baked goods, served in metal containers.

1. Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
Edwardsville
9.2 out of 10, Wonderful, (934 reviews)
Travellers love this hotel's courteous staff and pristine condition. Recharge with a free breakfast before exploring nearby attractions, or swim year-round in the indoor pool. The fitness centre, free WiFi and parking enhance your Edwardsville visit.
The price is RM486
RM559 total
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Express & Suites Edwardsville by IHG
A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

2. Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
Edwardsville
8.4 out of 10, Very good, (991 reviews)
Dive into the indoor pool or energise at the 24-hour fitness centre after exploring nearby Vadalabene Centre. Free breakfast, WiFi, and parking enhance your stay while the notably helpful staff ensures comfort in this quiet, central location.
The price is RM354
RM407 total
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn Edwardsville - St. Louis
A Hampton Inn & Suites hotel with a modern design, featuring a prominent entrance and a clear sky in the background.

3. Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
2.5 star property
Alton
9.0 out of 10, Wonderful, (725 reviews)
Just 9 minutes from Alton Station, this welcoming hotel offers an indoor pool and fitness centre. Explore nearby Alton Square Mall and Robert Wadlow Statue, then return to clean, comfortable rooms. Free breakfast, WiFi, and parking enhance your stay.
The price is RM499
RM568 total
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites St. Louis/Alton
A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

4. Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
Edwardsville
8.6 out of 10, Excellent, (766 reviews)
Enjoy this welcoming hotel near Edwardsville Arts Centre where hiking paths await your exploration. The fitness centre keeps you active while free breakfast, WiFi, and parking add extra value to your stay. Friendly staff receive consistent praise from visitors.
The price is RM526
RM605 total
includes taxes & fees
15 Nov - 16 Nov
Country Hearth Inn & Suites Edwardsville St. Louis
A Fairfield by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

5. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
3.0 star property
Granite City
9.2 out of 10, Wonderful, (537 reviews)
Nestled in Granite City, this hotel welcomes travellers with an indoor pool and fitness centre. Just minutes from Lewis and Clark Interpretive Centre, guests enjoy free breakfast, WiFi, and parking. The friendly staff receives consistent praise from past visitors.
The price is RM455
RM505 total
includes taxes & fees
29 Nov - 30 Nov
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.

6. Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
Granite City
7.8 out of 10, Good, (753 reviews)
Surrounded by scenic paths, this Granite City hotel offers complimentary breakfast, WiFi, and parking. Nature enthusiasts appreciate the nearby hiking and biking trails, while helpful staff ensure a comfortable stay near local attractions.
The price is RM294
RM333 total
includes taxes & fees
15 Nov - 16 Nov
Red Lion Inn & Suites Pontoon Beach
A hotel room with a bed, a sofa, a desk, and a television.

7. La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
3.0 star property
Granite City
7.6 out of 10, Good, (563 reviews)
Minutes from Mississippi River, this hotel offers a serene atmosphere with complimentary breakfast and free parking. Take a swim in the indoor pool, work out at the fitness centre, or enjoy peaceful, clean accommodation near Horseshoe Lake State Park.
The price is RM404
RM464 total
includes taxes & fees
16 Nov - 17 Nov
La Quinta Inn & Suites by Wyndham Pontoon Beach
A hotel entrance with a covered driveway and a parking area.

8. Best Western Plus Parkway Hotel

Best Western Plus Parkway Hotel
2.5 star property
Alton
8.2 out of 10, Very good, (1,000 reviews)
Relax in this welcoming Alton hotel where clean rooms and a helpful staff set the tone. Take a refreshing dip in the seasonal outdoor pool, or get your workout in at the fitness centre. Enjoy free breakfast, WiFi, and parking before exploring nearby attractions.
The price is RM366
RM418 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Plus Parkway Hotel
A modern lobby with a stone wall, seating area, and a fireplace.

9. The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel
3.0 star property
Alton
7.8 out of 10, Good, (825 reviews)
Located near Alton Station, this hotel offers a refreshing indoor pool and convenient dining at Chapala restaurant. After exploring nearby Robert Wadlow Statue, unwind at the bar or energise in the fitness centre. Rooms include microwaves and refrigerators.
The price is RM373
RM425 total
includes taxes & fees
13 Dec - 14 Dec
The Great Rivers, an Ascend Collection Hotel
A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

10. Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
Eastport
9.6 out of 10, Exceptional, (1,002 reviews)
The price is RM400
RM460 total
includes taxes & fees
29 Nov - 30 Nov
Drury Inn & Suites St. Louis Collinsville
A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and a landscaped area with trees.

11. Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG
2.5 star property
Alton
9.0 out of 10, Wonderful, (251 reviews)
This peaceful hotel offers free WiFi, parking, and daily buffet breakfast. Just 10 minutes from Alton Station and close to Alton Square Mall. Enjoy the 24-hour fitness centre after exploring Robert Wadlow Statue nearby.
The price is RM499
RM568 total
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Express and Suites Alton St Louis Area by IHG
An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.

12. Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
Troy
8.2 out of 10, Very good, (1,003 reviews)
Minutes from Bella Vista and Villa Marie wineries, this Troy hotel offers free parking and WiFi. Guests love the helpful staff and clean rooms. Take a refreshing swim in the indoor pool after exploring nearby St. Louis attractions.
The price is RM260
RM289 total
includes taxes & fees
15 Dec - 16 Dec
Super 8 by Wyndham Troy IL/St. Louis Area
A buffet area with a wooden counter, various food items, and a coffee station.

13. Comfort Inn Collinsville near St. Louis

Comfort Inn Collinsville near St. Louis
2.5 star property
Eastport
8.6 out of 10, Excellent, (1,000 reviews)
Unwind in a serene atmosphere near St. Louis with a warm indoor pool and comfortable beds. This hotel offers free breakfast, WiFi, and parking, just a 15-minute drive from America's Centre and within reach of Busch Stadium and Gateway Fun Park.
The price is RM393
RM451 total
includes taxes & fees
6 Dec - 7 Dec
Comfort Inn Collinsville near St. Louis
A hotel dining area with a buffet setup, including coffee makers and a potted plant.

14. Hampton Inn Collinsville

Hampton Inn Collinsville
2.5 star property
Eastport
8.4 out of 10, Very good, (742 reviews)
This Collinsville hotel offers an indoor pool and 24-hour fitness centre, plus convenient free breakfast, WiFi, and parking. Located near Splash City Family Waterpark and just a 15-minute drive from America's Centre Convention Complex, travellers praise the helpful staff.
The price is RM393
RM451 total
includes taxes & fees
6 Dec - 7 Dec
Hampton Inn Collinsville
A rooftop terrace with wicker chairs and a glass balustrade overlooking a bridge.

15. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.6 out of 10, Exceptional, (3,837 reviews)
Just steps from Gateway Arch and Busch Stadium, this hotel combines comfort with convenience. Enjoy the indoor pool, hot tub, and free breakfast before exploring St. Louis. With subway stations nearby and in-room refrigerators, your city adventure awaits.
The price is RM551
RM644 total
includes taxes & fees
15 Dec - 16 Dec
Drury Plaza Hotel St. Louis at the Arch
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

16. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1,018 reviews)
The price is RM447
RM555 total
includes taxes & fees
6 Dec - 7 Dec
Hyatt Select St. Louis Airport
A multi-story hotel with a covered entrance, stone pillars, and a parking lot.

17. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
3.0 star property
Eastport
7.4 out of 10, Good, (1,000 reviews)
Just 15 minutes from America's Centre, this Collinsville hotel offers a seasonal outdoor pool and fitness centre. Guests praise the clean rooms and helpful staff. Enjoy complimentary breakfast, WiFi, and parking, with Splash City Waterpark nearby.
The price is RM350
RM403 total
includes taxes & fees
22 Nov - 23 Nov
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
A lobby with a chandelier, seating area, and a reception desk.

18. Red Roof Inn St Louis - Troy, IL

Red Roof Inn St Louis - Troy, IL
2.0 star property
Troy
7.8 out of 10, Good, (1,004 reviews)
Located just outside St. Louis in Troy, IL, this welcoming hotel offers free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool before exploring nearby Bella Vista and Villa Marie wineries. Clean rooms and helpful staff ensure a comfortable visit.
The price is RM264
RM293 total
includes taxes & fees
24 Nov - 25 Nov
Red Roof Inn St Louis - Troy, IL
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

19. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,368 reviews)
Refreshing indoor pool awaits at this city centre St. Louis hotel, near both Convention Centre Station and Gateway Arch. Enjoy American cuisine at Atrium Restaurant & Bar, complimentary breakfast, and modern rooms with refrigerators and sofa beds.
The price is RM430
RM512 total
includes taxes & fees
10 Dec - 11 Dec
Embassy Suites by Hilton St. Louis Downtown
An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

20. Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
O'Fallon
9.6 out of 10, Exceptional, (1,006 reviews)
Splash into comfort at this O'Fallon retreat offering both indoor and outdoor pools. Located near O'Fallon Family Sports Park and St. Clair Bowl, this hotel combines fitness facilities with traveler-praised breakfast and helpful staff.
The price is RM416
RM483 total
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites St. Louis O'Fallon, IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Go beyond your typical stay in Roxana

pet-friendly image
Pet friendly
Pet friendly
Pool image
Pool
Pool

Top landmarks in Roxana

Wood River Refinery History Museum

Wood River Refinery History Museum is 0.8 mi (1.3 km) from central Roxana, why not stop by during your stay? If you want to experience more of the culture Roxana has to offer, head to Lewis and Clark Confluence Tower, Lewis and Clark Interpretive Center, and Jones-Confluence Point State Park.
See properties

Frequently Asked Questions

How much does a hotel room cost in Roxana?

You can find top hotels in Roxana from RM 260 with options to suit your budget and needs. If you're looking for an affordable hotel in Roxana that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Roxana hotels?

Discover great deals on Roxana hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Roxana hotels.

Can I book Roxana hotels with free cancellation?

To book a refundable Roxana hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central Roxana?

If you're looking for hotels in central Roxana, check out TownePlace Suites by Marriott St. Louis Edwardsville, IL and Bel Air Motel. Travellers love TownePlace Suites by Marriott St. Louis Edwardsville, IL for its location, as well as the indoor pool, free buffet breakfast and 24-hour gym this hotel offers. Bel Air Motel is another popular central motel with free parking, plus free WiFi in the guestrooms.

Keep exploring