Hotels in Old Appleton

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Top 5 hotels in Old Appleton at a glance

Drury Plaza Hotel Cape Girardeau Conference Center — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
The Riverview — 4-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
Drury Inn & Suites Jackson MO — 3-star hotel in Jackson. Guest rating: 9.6/10 — Exceptional.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau — 3-star hotel in Jackson. Guest rating: 9.0/10 — Wonderful.
Drury Inn & Suites Cape Girardeau — 3-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.

Where to stay in Old Appleton?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Old Appleton on Hotels.com. These Old Appleton hotels consistently deliver on comfort, location and traveler experience. Last updated on August 14, 2026.

Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

$100 nightly

$113 total

Aug 23 - Aug 24

Total with taxes and fees

Jackpot Suite | Living area | LED TV, Netflix, Hulu, first-run movies

Grand Riverview Two Queen Room | Premium bedding, pillowtop beds, in-room safe, desk

The Riverview

Cape Girardeau

$106 nightly

$120 total

Aug 18 - Aug 19

Total with taxes and fees

Desk, laptop workspace, blackout drapes, iron/ironing board

Drury Inn & Suites Jackson MO

Jackson

$80 nightly

$85 total

Aug 23 - Aug 24

Total with taxes and fees

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$93 nightly

$100 total

Aug 16 - Aug 17

Total with taxes and fees

Drury Inn & Suites Cape Girardeau

Cape Girardeau

$90 nightly

$102 total

Aug 21 - Aug 22

Total with taxes and fees

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

$114 nightly

$127 total

Aug 23 - Aug 24

Total with taxes and fees

Suite, 1 Bedroom (Feature) | Premium bedding, down comforters, pillowtop beds, in-room safe

Indoor pool, open 8 AM to 11 PM, sun loungers

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

$103 nightly

$116 total

Sep 13 - Sep 14

Total with taxes and fees

Desk, laptop workspace, blackout drapes, cribs (free)

Room, 2 Queen Beds, Accessible (Tub) | Desk, laptop workspace, blackout drapes, cribs (free)

Pear Tree Inn Cape Girardeau West

Cape Girardeau

$72 nightly

$81 total

Aug 23 - Aug 24

Total with taxes and fees

In-room safe, desk, blackout drapes, soundproofing

Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

$83 nightly

$99 total

Aug 23 - Aug 24

Total with taxes and fees

Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

$85 nightly

$95 total

Aug 24 - Aug 25

Total with taxes and fees

Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

$125 nightly

$142 total

Aug 24 - Aug 25

Total with taxes and fees

Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)

Tru By Hilton Cape Girardeau

Cape Girardeau

$89 nightly

$102 total

Aug 23 - Aug 24

Total with taxes and fees

Egyptian cotton sheets, premium bedding, down comforters

Quality Inn Cape Girardeau North

Cape Girardeau

$62 nightly

$70 total

Sep 6 - Sep 7

Total with taxes and fees

Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, cribs (free)

Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

$106 nightly

$119 total

Aug 20 - Aug 21

Total with taxes and fees

Holiday Inn Express & Suites Perryville by IHG

Perryville

$91 nightly

$104 total

Sep 13 - Sep 14

Total with taxes and fees

Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Baymont by Wyndham Chester IL

Chester

$73 nightly

$81 total

Aug 30 - Aug 31

Total with taxes and fees

Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes

Super 8 by Wyndham Perryville

Perryville

$68 nightly

$78 total

Sep 1 - Sep 2

Total with taxes and fees

Suite 11, 1 Queen Bed with Sofa bed, Pets Allowed | Interior

The Atrium - A Boutique Hotel

Perryville

$158 nightly

$181 total

Aug 16 - Aug 17

Total with taxes and fees

Deluxe Double Room | Premium bedding, iron/ironing board (on request), WiFi (free)

EC Reed's Mercantile and Hotel

Marble Hill

$84 nightly

$92 total

Aug 15 - Aug 16

Total with taxes and fees

Coffee/tea maker, full-size fridge, microwave, oven

55-inch Smart TV with digital channels, TV, streaming services

Urban Loft 1 | Egyptian cotton sheets, premium bedding, down comforters

Urban Lofts

Perryville

$293 nightly

$335 total

Aug 21 - Aug 22

Total with taxes and fees

View all properties

Go beyond your typical stay in Old Appleton

Pet friendly

Pool

Check out reviews of Old Appleton hotels guests love

Drury Inn & Suites Jackson MO

10/10 Excellent

"The kick-back after a day of travel is a most welcome amenity, and the breakfast is always great. Drury is our favorite place to stay."

Tru By Hilton Cape Girardeau

10/10 Excellent

"Clean"

Perryville RV Resort

10/10 Excellent

"Great time"

Super 8 by Wyndham Perryville

10/10 Excellent

"Super 8 is my go to when I need to get a room."

The Atrium - A Boutique Hotel

10/10 Excellent

"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."

Frequently asked questions

How much does a hotel room cost in Old Appleton?

You can find top hotels in Old Appleton from $70 with options to suit your budget and needs. If you're after an affordable hotel in Old Appleton that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Old Appleton hotels?

Discover great deals on Old Appleton hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Old Appleton hotels.

Can I book Old Appleton hotels with free cancellation?

To book a refundable Old Appleton hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book a refundable hotel in Old Appleton?

If you're looking for the flexibility to change your travel plans to Old Appleton, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Old Appleton be like during my visit?

The warmest months in Old Appleton are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 40°F. The rainiest months are April and March.

Why should I book my Old Appleton hotel through Hotels.com?

There are plenty of reasons to book your Old Appleton travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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