Mytilene Hotel Accommodation

October 2026
13
November 2026

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Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Where to stay in Mytilene?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Mytilene on Hotels.com. These Mytilene hotels consistently deliver on quality, location and traveller experience. Last updated on 13 October 2026.

1. Hotel Lesvion

Hotel Lesvion
Lesvos
RM309
RM361 total
includes taxes & fees
25 Oct - 26 Oct
Hotel Lesvion

2. Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
RM500
RM561 total
includes taxes & fees
9 Nov - 10 Nov
Theofilos Paradise Boutique Hotel

3. Heliotrope Hotels

Heliotrope Hotels
Lesvos
RM348
RM427 total
includes taxes & fees
15 Oct - 16 Oct
Heliotrope Hotels

4. Heliotrope The Studios

Heliotrope The Studios
Lesvos
RM348
RM391 total
includes taxes & fees
14 Oct - 15 Oct
Heliotrope The Studios

5. Elysion Hotel

Elysion Hotel
Lesvos
RM396
RM502 total
includes taxes & fees
14 Oct - 15 Oct
Elysion Hotel

6. Loriet Hotel

Loriet Hotel
Lesvos
RM343
RM389 total
includes taxes & fees
1 Nov - 2 Nov
Loriet Hotel

7. Akti Vigla Premium

Akti Vigla Premium
Lesvos
RM260
RM287 total
includes taxes & fees
2 Nov - 3 Nov
Akti Vigla Premium

8. Elies Residences

Elies Residences
Lesvos
RM449
RM501 total
includes taxes & fees
14 Oct - 15 Oct
Elies Residences

9. Aklidi Hotel

Aklidi Hotel
Lesvos
RM419
RM482 total
includes taxes & fees
14 Oct - 15 Oct
Aklidi Hotel

10. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
RM384
RM439 total
includes taxes & fees
1 Nov - 2 Nov
Mythical Coast Wellness Retreat

11. Lasia Hotel

Lasia Hotel
Lesvos
RM277
RM350 total
includes taxes & fees
14 Oct - 15 Oct
Lasia Hotel

12. Agora Apartments

Agora Apartments
Lesvos
RM367
RM411 total
includes taxes & fees
15 Oct - 16 Oct
Agora Apartments

13. Sofie's Choice Mytilini

Sofie's Choice Mytilini
Lesvos
RM354
RM424 total
includes taxes & fees
21 Oct - 22 Oct
Sofie's Choice Mytilini

14. Ampoulos Rooms & Apartments

Ampoulos Rooms & Apartments
Lesvos
RM524
RM583 total
includes taxes & fees
14 Oct - 15 Oct
Ampoulos Rooms & Apartments

15. Oikies Small Elegant Houses

Oikies Small Elegant Houses
Lesvos
RM416
RM465 total
includes taxes & fees
14 Oct - 15 Oct
Oikies Small Elegant Houses

16. Paradisos studios

Paradisos studios
Lesvos
RM135
RM157 total
includes taxes & fees
14 Oct - 15 Oct
Paradisos studios

17. Galazio Asteri I

Galazio Asteri I
Lesvos
RM225
RM255 total
includes taxes & fees
27 Oct - 28 Oct
Galazio Asteri I

18. Olive Green Studios and Apartments

Olive Green Studios and Apartments
Lesvos
RM288
RM325 total
includes taxes & fees
16 Oct - 17 Oct
Olive Green Studios and Apartments

19. Imerti Hotel

Imerti Hotel
Lesvos
RM416
RM478 total
includes taxes & fees
30 Oct - 31 Oct
Imerti Hotel

20. Shine Studios

Shine Studios
Lesvos
RM225
RM255 total
includes taxes & fees
15 Oct - 16 Oct
Shine Studios
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Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
We have 1 left at
RM528
per night
RM1,247 total
includes taxes & fees
Theofilos Paradise Boutique Hotel

Hotel Lesvion

Hotel Lesvion
Lesvos
We have 1 left at
RM535
per night
RM1,218 total
includes taxes & fees
Hotel Lesvion

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
RM255 off
RM398
per night
RM1,008 total
includes taxes & fees
Mythical Coast Wellness Retreat

Elysion Hotel

Elysion Hotel
Lesvos
We have 2 left at
RM388
per night
RM987 total
includes taxes & fees
Elysion Hotel

Loriet Hotel

Loriet Hotel
Lesvos
RM414
per night
RM998 total
includes taxes & fees
Sign in for extra savings
Loriet Hotel

Hotel Lesvion

Hotel Lesvion
Lesvos
We have 2 left at
RM407
per night
RM453 total
includes taxes & fees
Hotel Lesvion

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
We have 4 left at
RM552
per night
RM618 total
includes taxes & fees
Theofilos Paradise Boutique Hotel

Elysion Hotel

Elysion Hotel
Lesvos
We have 3 left at
RM513
per night
RM581 total
includes taxes & fees
Elysion Hotel

Loriet Hotel

Loriet Hotel
Lesvos
RM343
per night
RM389 total
includes taxes & fees
Sign in for extra savings
Loriet Hotel

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
RM52 off
RM465
per night
RM528 total
includes taxes & fees
Mythical Coast Wellness Retreat

Check out pet-friendly hotels in Mytilene

Heliotrope Hotels

Heliotrope Hotels
Lesvos
RM348
RM427 total
includes taxes & fees
15 Oct - 16 Oct
Heliotrope Hotels

Loriet Hotel

Loriet Hotel
Lesvos
RM343
RM389 total
includes taxes & fees
1 Nov - 2 Nov
Loriet Hotel

Heliotrope The Studios

Heliotrope The Studios
Lesvos
RM348
RM391 total
includes taxes & fees
14 Oct - 15 Oct
Heliotrope The Studios

Agora Apartments

Agora Apartments
Lesvos
RM367
RM411 total
includes taxes & fees
15 Oct - 16 Oct
Agora Apartments

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
RM500
RM561 total
includes taxes & fees
9 Nov - 10 Nov
Theofilos Paradise Boutique Hotel

Paradisos studios

Paradisos studios
Lesvos
RM135
RM157 total
includes taxes & fees
14 Oct - 15 Oct
Paradisos studios

Galazio Asteri I

Galazio Asteri I
Lesvos
RM225
RM255 total
includes taxes & fees
27 Oct - 28 Oct
Galazio Asteri I
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You can also stay at hotels with a pool in Mytilene

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
RM500
RM561 total
includes taxes & fees
9 Nov - 10 Nov
Theofilos Paradise Boutique Hotel

Heliotrope Hotels

Heliotrope Hotels
Lesvos
RM348
RM427 total
includes taxes & fees
15 Oct - 16 Oct
Heliotrope Hotels

Loriet Hotel

Loriet Hotel
Lesvos
RM343
RM389 total
includes taxes & fees
1 Nov - 2 Nov
Loriet Hotel

Elies Residences

Elies Residences
Lesvos
RM449
RM501 total
includes taxes & fees
14 Oct - 15 Oct
Elies Residences

Elysion Hotel

Elysion Hotel
Lesvos
RM396
RM502 total
includes taxes & fees
14 Oct - 15 Oct
Elysion Hotel

Lasia Hotel

Lasia Hotel
Lesvos
RM277
RM350 total
includes taxes & fees
14 Oct - 15 Oct
Lasia Hotel

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
RM384
RM439 total
includes taxes & fees
1 Nov - 2 Nov
Mythical Coast Wellness Retreat

Oikies Small Elegant Houses

Oikies Small Elegant Houses
Lesvos
RM416
RM465 total
includes taxes & fees
14 Oct - 15 Oct
Oikies Small Elegant Houses

Galazio Asteri I

Galazio Asteri I
Lesvos
RM225
RM255 total
includes taxes & fees
27 Oct - 28 Oct
Galazio Asteri I
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Go beyond your typical stay in Mytilene

Pool image
Pool
Pool
pet-friendly image
Pet friendly
Pet friendly
spa image
Spa
Spa
hot tub image
Hot tub
Hot tub
apart-hotel image
Apart hotel
Apart hotel
Apartment image
Apart­ment
Apart­ment
Family-friendly image
Family friendly
Family friendly
villa image
Villa
Villa

Top landmarks in Mytilene

Mytilini Castle

9.0/10 (25 reviews)
You might want to get your camera out and head to Mytilini Castle – just one of the landmarks located 1 mi (1.7 km) from central Mytilene.
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Thermes Gera Hot Springs

Thermes Gera Hot Springs is 4.1 mi (6.5 km) from central Mytilene, why not stop by during your stay?
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Thermi Beach

7.8/10 (18 reviews)
Whether you want to collect beach glass or watch the sunset, Thermi Beach is a spot you might want to check out when visiting central Pirgi Thermis. Catch the sunset by the shore at Plaz Kanóni, just a short walk away.
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Church of Taxiarches

10.0/10 (1 review)
Church of Taxiarches is 2.2 mi (3.5 km) from central Mytilene, why not stop by during your stay?
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Roman Aqueduct at Moria

8.0/10 (3 reviews)
If you're planning a bit of sightseeing during your trip, head to Roman Aqueduct at Moria – just one of the landmarks located 3 mi (4.9 km) from central Mytilene.
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Archaeological Site of Thermi

If you're planning a bit of sightseeing during your trip, head to Archaeological Site of Thermi – just one of the monuments in central Pirgi Thermis.
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St Hermogenes Charamida Lesvos

St Hermogenes Charamida Lesvos is just one of the landmarks located 5.6 mi (9.1 km) from central Mytilene, so you might want to stop by for a few pics during your trip.
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Theophilos Museum

If museums are on your list of things to see, then you might want to head to Theophilos Museum, located in the heart of Varia. If you want to see more of the museums in Varia, Ecclesiastical Byzantine Museum and Theriade Library and Museum of Modern Art aren't far.
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Learn more about Mytilene

Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.

See all hotels in Mytilene
A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Frequently Asked Questions

How much does a hotel room cost in Mytilene?

You can discover great hotels in Mytilene from RM 134 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Mytilene that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Mytilene hotels?

Discover great deals on Mytilene hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Mytilene hotels.

Can I book Mytilene hotels with free cancellation?

To book a refundable Mytilene hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are the top-rated luxury hotels in Mytilene?

Some of the most popular luxury hotels in Mytilene are Theofilos Paradise Boutique Hotel, Mythical Coast Wellness Retreat, and Elysion Hotel. Theofilos Paradise Boutique Hotel is a luxury hotel with a high guest rating amongst our travellers, and it offers 4 hot springs, a full-service spa and a seasonal outdoor pool. Mythical Coast Wellness Retreat and Elysion Hotel are also popular luxury stays in great Mytilene locations.

What are some of the best Mytilene beach hotels?

For a beach holiday in Mytilene, Thermi Beach is a top place to visit. Pick a well-reviewed Mytilene beach hotel to maximise your holiday. Check out Mythical Coast Wellness Retreat if you're after a hotel that's near the water. With a beach and guestrooms offering furnished balconies, our travellers rate it highly at 8.6 out of 10.

What are some top pet-friendly hotels in Mytilene?

Our travellers' favourite pet-friendly hotels in Mytilene include:

You can check "Pet friendly" on the Hotels.com "Amenities" filter in your search to find even more pet-friendly hotels in Mytilene.

What are some of the best hotels in Mytilene for couples?

Enjoy your couple's retreat with a stay at a top-rated Mytilene romantic hotel. Our travellers love Elysion Hotel, a hotel with 2 restaurants. Another romantic hotel with top reviews is Mythical Coast Wellness Retreat. This hotel offers a beach and 5 restaurants for a perfect stay. Use the "Traveller experience" filter in your search and select "Adults only" or "Romantic" to find even more hotels in Mytilene for couples on Hotels.com.

What are the top Mytilene hotels with a pool?

For some added luxury, discover the best Mytilene hotels with a pool. Theofilos Paradise Boutique Hotel is a great hotel with a seasonal outdoor pool and a children's pool, and a guest rating of 9.6 out of 10. Plus, you can make the most of its 4 hot springs. Elysion Hotel is a popular hotel that features an outdoor pool along with a children's pool. You can select "Pool" in the "Amenities" filter of your search on Hotels.com to find even more places to stay in Mytilene with a pool.

What are some of the best Mytilene hotels with free parking?

If you're arriving by car, choosing a great Mytilene hotel with free parking is a plus. Our travellers' favourites include:

What are the top Mytilene boutique hotels?

Treat yourself to a stylish and luxurious boutique hotel in Mytilene. Theofilos Paradise Boutique Hotel is a popular hotel with our travellers, offering guests a seasonal outdoor pool as well as individually furnished guestrooms with down comforters.

What are some popular hotels in central Mytilene?

If you're looking for hotels in central Mytilene, check out Theofilos Paradise Boutique Hotel and Hotel Lesvion. Travellers love Theofilos Paradise Boutique Hotel for its location, as well as the seasonal outdoor pool, children's pool and 4 hot springs this hotel offers. Hotel Lesvion is another popular central hotel with a restaurant, a bar/lounge and a free buffet breakfast.

Find out more about Mytilene

Whispers of the Past: Unearth the Treasures of Mytilene's Timeless Charm

Discover Mytilene, the charming capital of Lesvos, Greece, where history meets modern allure. Wander through captivating museums and explore the ancient ruins and monuments that whisper tales of bygone eras. Marvel at the impressive Mytilene Castle and soak in the panoramic views of the bustling port. Stroll along the scenic waterfront and enjoy local shopping treasures. With its unique blend of cultural heritage and vibrant city life, Mytilene offers an unforgettable experience for every traveller seeking a taste of authentic Greek charm.

Discover great hotels near Mytilene

Mytilene offers a range of comfortable hotel accommodations, from luxury properties with stunning views to cosy boutique stays. Guests enjoy quality beds, stylish rooms and impressive dining, ensuring a memorable visit to this vibrant North Aegean destination. Here are some of the best hotels near Mytilene that our travelers love:

  1. Ariadnes Holiday Accommodationopens in new window: This 3.0-star guesthouse offers travellers a beach holiday with direct access to the sun-kissed shores. It is highly regarded for its exceptional ambience and appealing design that complements a relaxed coastal lifestyle. The hotel's standout feature is its seamless connection to the beach, contributing to a smooth, high-quality journey for leisure travellers. The property exudes a boutique charm with a focus on modern comfort and curated experiences, ensuring a memorable stay with appealing architectural details and stylish amenities.
  2. Ariadnes Holiday Accommodation IIopens in new window: This 3.0-star guesthouse delivers a vibrant beach holiday experience with direct beach access, ideal for leisure travellers seeking a distinctive coastal retreat. The property shines with its elegant design and curated, high-end experiences that ensure a consistently smooth and refined journey. Emphasising a blend of comfort and stylish amenities, Ariadnes Holiday Accommodation II offers a sophisticated escape where travellers can indulge in a memorable stay enriched by well-thought-out details and expressive architectural features.
  3. Aeolis Apartments & Studiosopens in new window: This 3.0-star guesthouse provides a unique hot spring themed and spa-focussed holiday, offering a natural hot spring nearby for an exceptional wellness escape. Perfect for leisure travellers, the property boasts a full spa and pool service featuring Swedish massage, reflexology, and couples treatment rooms, ensuring a rejuvenating experience. The hotel's design harmoniously blends modern aesthetics with therapeutic elements, delivering an immersive, high-quality journey enriched by luxurious spa treatments and a sophisticated, boutique setting.

Where to stay in Mytilene

Some of the best areas to stay in Mytilene, Lesvos are Lesvos, Neapoli, and Varia. Lesvos boasts stunning beaches, rich history with museums and ruins, and a charming marina. Neapoli offers friendly locals and beautiful beaches, perfect for relaxation. Varia is ideal for enjoying sea views, coffee culture, and live music. For first-time visitors, Lesvos is the best choice, providing a well-rounded experience.

  1. Lesvosopens in new window: Lesvos is a fantastic base for travellers looking to explore rich history and stunning landscapes. With its charming small towns, beautiful countryside, and captivating ruins, it offers a unique blend of culture and relaxation. Key attractions like the Monastery of Saint Raphael and Molyvos Castle showcase the island's rich heritage. You can also unwind at the sandy beaches or stroll along the marina, soaking in the vibrant atmosphere. For those seeking a touch of luxury, there are upscale accommodations that provide exceptional service and stunning views, making Lesvos a perfect getaway.
  2. Neapoliopens in new window: Neapoli is known for its friendly locals and beautiful beach vibes, making it an inviting spot for a laid-back holiday. The area boasts picturesque coastal views and a welcoming atmosphere, perfect for relaxation. Enjoy the sun-soaked beaches, where you can engage in leisurely activities or simply bask in the sun. Neapoli is a great choice for visitors looking to experience the island’s charm while enjoying a friendly community feel, making it a delightful place to unwind.
  3. Variaopens in new window: Varia is a tranquil area that captures the essence of island life, where you can enjoy serene seaside views and a relaxed atmosphere. This small town is perfect for visitors who appreciate coffee culture and live music, with various cafés and bars offering a delightful retreat. The local scenery is picturesque, making it ideal for leisurely strolls. Varia is perfect for those wanting to experience a mix of relaxation and cultural charm, all while being close to the sea.

Things to do in Mytilene

Mytilene beckons with its stunning coastal landscapes, framed by azure waters and lush hills. Explore its rich history through ancient ruins and captivating museums, or wander along picturesque beaches and vibrant waterfronts. With delightful parks and scenic vistas, it’s an ideal spot for relaxation and discovery.

  • Monastery of Saint Raphaelopens in new window – Visit this serene monastery, a significant religious site, known for its stunning architecture and tranquil surroundings. It offers a peaceful retreat where you can reflect and appreciate the local spirituality.
  • Molyvos Castleopens in new window – Climb to the top of Molyvos Castle for breathtaking panoramic views of the village and the sea. This historic fortress, with its impressive stone walls, tells tales of ancient battles and provides a glimpse into the island's rich past.
  • Mólyvosopens in new window – Spend a relaxing day at Mólyvos beach, where you can bask in the sun, take a refreshing swim, or enjoy beachside cafés and restaurants. The scenic views and charming atmosphere make it a perfect spot for unwinding.
  • Eftalou Hot Springsopens in new window – Experience the healing waters at Eftalou Hot Springs. A dip in these natural thermal springs promises relaxation and rejuvenation, surrounded by beautiful landscapes.
  • Teriade Museumopens in new window – Explore a diverse collection of modern art at the Teriade Museum, featuring works from prominent artists. The museum combines cultural heritage with contemporary creativity, making it a delightful stop for art enthusiasts.

4 tips for savvy savings when booking a hotel in Mytilene

  1. Book for the cheapest times: The most budget-friendly time to visit Mytilene is during February, November, and December, when hotel prices are generally lower. To fully appreciate the significant historical and cultural landmarks, such as museums, churches, ruins, and the impressive castle, a stay of at least 4 to 5 days is recommended. This duration allows visitors to explore the rich architecture, scenic marina, and beautiful islands, making for a trip that is great value for money. Additionally, prices may drop during these months, making it a perfect opportunity for those travelling on a budget.
  2. Look for last-minute deals on Hotels.com: For Mytilene hotel deals, you may discover attractive offers by visiting the Dealsopens in new window section on Hotels.com. If you're planning a spontaneous escape, you could find discounted rates by checking the Last-Minute Deals section. Additionally, the Smart Shopping tool in the Hotels.com app may help you compare hotel prices and amenities, keeping you informed about any available opportunities for savings. Stay alert with email notifications to ensure you're among the first to know when prices drop or rooms become available.
  3. Be flexible with dates: Prices may fluctuate depending on factors such as the hotel's location, star rating, and the time of year, so being flexible with your travel dates could help you find a better deal on your stay at a hotel in Mytilene. For those seeking something distinctive, boutique hotels can provide a more personalised experience and at times, greater value. When you book through Hotels.com, we’ll inform you whether the price for your chosen dates is above or below the average. If the price appears to be on the higher side, we may suggest alternative dates that could offer a more affordable option.
  4. Consider your location: Opting for accommodation nearer to main attractions or city centres may offer convenience, but it often tends to come with higher prices. For more budget-friendly options, consider hotels in less central areas or neighbourhoods, striking a balance between cost and accessibility to the sites you wish to visit. You might also look into independent hotels located further afield, which are more likely to provide a more authentic and economical experience.

Best time to go to Mytilene

Mytilene experiences its lowest average temperature in January, at 49.3°F (9.6°C), while August is the hottest month, with an average temperature of 80.1°F (26.7°C). January is typically the wettest month. If you’re looking to soak up the lively atmosphere in Mytilene, July to September are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is sunny, with no rainfall. However, if you prefer a more relaxed experience, January, February, and December are perfect for a quieter getaway, marked by light rainfall and mostly sunny conditions.

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