Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on quality, location and traveller experience. Last updated on .
Cape Girardeau Hotel Accommodation

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1. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,007 reviews)
The price is RM406
RM458 total
includes taxes & fees
8 Nov - 9 Nov

2. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (239 reviews)
The price is RM410
RM463 total
includes taxes & fees
8 Nov - 9 Nov

3. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.2 out of 10, Wonderful, (1,002 reviews)
The price is RM292
RM330 total
includes taxes & fees
8 Nov - 9 Nov

4. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
The price is RM402
RM457 total
includes taxes & fees
30 Nov - 1 Dec

5. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
The price is RM365
RM412 total
includes taxes & fees
8 Nov - 9 Nov

6. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (699 reviews)
The price is RM464
RM523 total
includes taxes & fees
3 Nov - 4 Nov

7. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (556 reviews)
The price is RM471
RM534 total
includes taxes & fees
15 Nov - 16 Nov

8. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (856 reviews)
The price is RM396
RM447 total
includes taxes & fees
8 Nov - 9 Nov

9. Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
8.0 out of 10, Very good, (1,000 reviews)
The price is RM288
RM347 total
includes taxes & fees
22 Nov - 23 Nov

10. Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.0 out of 10, Good, (816 reviews)
The price is RM241
RM272 total
includes taxes & fees
8 Nov - 9 Nov

11. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, Good, (682 reviews)
The price is RM238
RM267 total
includes taxes & fees
1 Dec - 2 Dec

12. Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.4 out of 10, Good, (296 reviews)
The price is RM279
RM310 total
includes taxes & fees
15 Nov - 16 Nov

13. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, Good, (443 reviews)
The price is RM270
RM302 total
includes taxes & fees
4 Nov - 5 Nov

14. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (890 reviews)
The price is RM324
RM351 total
includes taxes & fees
8 Nov - 9 Nov

16. Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
8.0 out of 10, Very good, (785 reviews)
The price is RM307
RM332 total
includes taxes & fees
22 Nov - 23 Nov

17. Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, Good, (107 reviews)
The price is RM268
RM300 total
includes taxes & fees
3 Nov - 4 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Cape Girardeau
Family friendly
Top landmarks in Cape Girardeau
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

Check out reviews of Cape Girardeau hotels guests love

The Riverview
10/10 Excellent
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