Seneca Hotel Accommodation

October 2026
9
November 2026

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Check prices for these dates

This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Where to stay in Seneca?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Seneca on Hotels.com. These Seneca hotels consistently deliver on quality, location and traveller experience. Last updated on 9 October 2026.

1. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
RM504
RM555 total
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Seneca-Clemson Area

2. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
RM490
RM539 total
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites Seneca Clemson Univ Area

3. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
RM435
RM479 total
includes taxes & fees
18 Oct - 19 Oct
Tru by Hilton Seneca Clemson

4. Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
RM414
RM455 total
includes taxes & fees
12 Oct - 13 Oct
Best Western Seneca-Clemson

5. Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
RM446
RM553 total
includes taxes & fees
18 Oct - 19 Oct
Lakeside Lodge Clemson

6. Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
RM309
RM365 total
includes taxes & fees
18 Oct - 19 Oct
Quality Inn Seneca US-123

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
RM347
RM382 total
includes taxes & fees
19 Oct - 20 Oct
Days Inn by Wyndham Seneca / Clemson Area

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
RM379
RM596 total
includes taxes & fees
20 Oct - 21 Oct
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

9. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
RM854
RM948 total
includes taxes & fees
3 Nov - 4 Nov
The Shepherd Hotel Downtown Clemson

10. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
RM609
RM676 total
includes taxes & fees
18 Oct - 19 Oct
Clemson University's James F. Martin Inn

11. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
Clemson
RM527
RM585 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Express & Suites Clemson by IHG

12. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
RM659
RM732 total
includes taxes & fees
18 Oct - 19 Oct
The Abernathy of Clemson

13. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
RM431
RM478 total
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn & Suites Clemson - University Area

14. Courtyard Marriott Clemson

Courtyard Marriott Clemson
Clemson
RM438
RM486 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard Marriott Clemson

15. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
RM448
RM497 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Clemson-University Area

16. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
RM431
RM479 total
includes taxes & fees
11 Oct - 12 Oct
Best Western Plus Clemson Hotel & Conference Center

17. The Inn at Patrick Square

The Inn at Patrick Square
Clemson
RM609
RM676 total
includes taxes & fees
18 Oct - 19 Oct
The Inn at Patrick Square

18. Inn @ Clemson

Inn @ Clemson
Clemson
RM328
RM364 total
includes taxes & fees
11 Oct - 12 Oct
Inn @ Clemson

19. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
Walhalla
RM296
RM330 total
includes taxes & fees
8 Nov - 9 Nov
Rodeway Inn & Suites Walhalla

20. Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
Anderson
RM413
RM459 total
includes taxes & fees
29 Oct - 30 Oct
Country Inn & Suites by Radisson, Anderson, SC
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Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 1 left at
RM569
per night
RM626 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
RM426
per night
RM496 total
includes taxes & fees
Quality Inn Seneca US-123

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
We have 2 left at
RM651
per night
RM716 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
RM507
per night
RM558 total
includes taxes & fees
Best Western Seneca-Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
RM336
per night
RM369 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
We have 8 left at
RM446
per night
RM554 total
includes taxes & fees
Lakeside Lodge Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
We have 2 left at
RM630
per night
RM693 total
includes taxes & fees
Tru by Hilton Seneca Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 5 left at
RM896
per night
RM1,166 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 6 left at
RM385
per night
RM450 total
includes taxes & fees
Quality Inn Seneca US-123

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 3 left at
RM569
per night
RM626 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
We have 4 left at
RM679
per night
RM747 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
RM507
per night
RM558 total
includes taxes & fees
Best Western Seneca-Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
We have 7 left at
RM446
per night
RM554 total
includes taxes & fees
Lakeside Lodge Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
RM348
per night
RM383 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
We have 2 left at
RM569
per night
RM626 total
includes taxes & fees
Tru by Hilton Seneca Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 5 left at
RM937
per night
RM1,211 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

You may also like pet-friendly hotels in Seneca

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
RM446
RM553 total
includes taxes & fees
18 Oct - 19 Oct
Lakeside Lodge Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
RM435
RM479 total
includes taxes & fees
18 Oct - 19 Oct
Tru by Hilton Seneca Clemson

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
RM309
RM365 total
includes taxes & fees
18 Oct - 19 Oct
Quality Inn Seneca US-123

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
RM347
RM382 total
includes taxes & fees
19 Oct - 20 Oct
Days Inn by Wyndham Seneca / Clemson Area

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
RM379
RM596 total
includes taxes & fees
20 Oct - 21 Oct
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
View all properties

Go beyond your typical stay in Seneca

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Pet friendly
Pet friendly
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Hot tub
Hot tub
Pool image
Pool
Pool
cabin image
Cabin
Cabin
Apartment image
Apart­ment
Apart­ment
Family-friendly image
Family friendly
Family friendly
Cottage image
Cottage
Cottage
Condo image
Condo
Condo
villa image
Villa
Villa
Our prices for hotels in Seneca are cheapest in January

Price trends for hotels in Seneca

Pricing is based on two traveller single night rates
View properties in October

October

High 23°C / low 12°C. Sunny most days.
23°
12°
17°
6°
12°
4°
10°
1°
13°
3°
17°
6°
22°
10°
26°
15°
31°
19°
32°
21°
31°
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28°
18°
Monthly weather averages (˚C)

Top neighbourhoods in Seneca

Downtown

City centre Seneca charms visitors with well-preserved historical buildings that tell the storey of its railway heritage. The tree-lined Ram Cat Alley showcases local history through colourful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodation range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire city centre is walkable with wide pavements, making it easy to discover this authentic slice of small-town America at your own pace.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Holiday rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The area trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront holiday homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This area is all about authentic lakeside living without commercial distractions. Most travellers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy area in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in holiday rental homes with private yards and driveways. The area gets incredibly quiet after dark—ideal for travellers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
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Highpointe Field

Highpointe Field is worth a visit, located 5.6 mi (8.9 km) from central Seneca.
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Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.
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South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.
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Toy Train Park

Toy Train Park is worth a pic or two when discovering Downtown.
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World of Energy

If museums are on your list of things to see in Seneca, then you might want to head to World of Energy. If you want to experience more of the culture Seneca has to offer, head to Lake Keowee, Keowee Key Golf Course, and High Falls County Park.
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Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.
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Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic city centre offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

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A sunset over a lake surrounded by dense forests and residential areas.

Frequently Asked Questions

How much does a hotel room cost in Seneca?

You can find top hotels in Seneca from RM 295 with options to suit your budget and needs. If you're after an affordable hotel in Seneca that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Seneca hotels?

Discover great deals on Seneca hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Seneca hotels.

Can I book Seneca hotels with free cancellation?

It's easy to book a refundable Seneca hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some of the best Seneca hotels with free parking?

If you're exploring by car, finding a great Seneca hotel with free parking is a win. Our travellers' favourites include:

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